Dihydromyricetin is very significant to prevent the use of alcohol. It also helps in treating the hangover through two main mechanisms of action and those are:
- The use of DHM speeds up the pace of metabolizing alcohol and acetaldehyde in the human body.
- Proper doses of DHM control the effect alcohol on the GABA receptors of the brain.
When a person intake alcoholic drinks it directly find the way to the intestine. On the first hand it hits the stomach the most, then goes to the intestines and is very well absorbed into the blood stream lastly. Through the blood stream the alcohol reaches your liver. The lever metabolizes the consumed alcohol at a continuous rate regardless of the quantity consumed. But those alcohols which cannot be metabolized and goes directly to the brain cause some harmful effect for you.
Hence our body metabolizes the alcohol into acetaldehyde which is not a harmless substance. There is evidence which support the poisonous aspect of this acetaldehyde. It is in fact 10-30 times more toxic than the alcohol itself. So though alcohol is the primary source of the hangover the Symptoms of acetaldehyde poisoning is not less than nausea and intense headaches. Thus this is the main cause of hangover symptoms. This acetaldehyde further is broken down into acetic acid, which ultimately expelled from the body all the way through urine and breadth.
Dihydromyricetin works through increasing the ability of the enzymes known as acetaldehyde dehydrogenase (ALDH) and alcohol dehydrogenase (ADH) into the body. Alcohol metabolized into acetaldehyde with the help of alcohol dehydrogenase (ADH), while alcohol dehydrogenase (ADH) is responsible for further breaking down of acetaldehyde into acetic acid.
Thus an increased dose of DHM allows your body to flush all the toxin effect of the alcohol and the acetaldehyde at a faster rate. And in this way it helps in reducing the following morning hangover symptoms.
The excess alcohols which cannot be metabolised through your body get circulated to the brain through your blood stream and there it affects two different neurotransmitter, those are Glutamate and GABA. They are like the chemical messengers who control all your movement, emotions and behaviour.
So when you suddenly stop alcohol consumption after a heavy drink last night. The brain will take time to get normal. Hence as your brain was at a state of extreme depression and trying to come out of it to a state of slight arousal, it may demonstrate some symptoms like anxiety, trouble sleeping, headaches and trouble concentrating.
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